Lipitor can lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as age, smoking, high blood pressure, low HDL, or family history of early heart disease. Lipitor can lower the risk for heart attack or stroke in patients with diabetes and risk factors such as diabetic eye or kidney problems, smoking, or high blood pressure.
The most common side effects reported with Lipitor include diarrhea, upset stomach, muscle and joint pain, and changes in some blood tests. All patients starting therapy with Lipitor should be advised of the risk of myopathy and told to report promptly any unexplained muscle pain, tenderness, or weakness.
Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria presence of myoglobin in the urine have been reported with Lipitor and with other drugs in this class. The recommended starting dose of Lipitor is 10 or 20 mg once daily. The dosage range of Lipitor is 10 to 80 mg once daily. Lipitor can be administered as a single dose at any time of the day, with or without food. The dose of Lipitor should be individualized according to patient characteristics and goals of therapy.
Lipitor has not been studied in controlled clinical trials involving pre-pubertal patients or patients younger than 10 years of age. Lipitor is contraindicated in patients with active liver disease, pregnancy, and in nursing mothers. What is the difference between pravastatin versus Lipitor? Pravachol pravastatin sodium is a lipid-lowering compound, a statin, one of many HMG-CoA reductase inhibitors, which reduce cholesterol biosynthesis.
Pravachol produces its lipid-lowering effect in two ways. First, as a consequence of its reversible inhibition of HMG-CoA reductase activity, it effects modest reductions in intracellular pools of cholesterol.
This results in an increase in the number of LDL-receptors on cell surfaces and enhanced receptor-mediated catabolism and clearance of circulating LDL. Pravachol is indicated as adjunctive therapy to diet for the treatment of patients with elevated serum triglyceride levels. Pravachol is indicated for the treatment of patients with primary dysbetalipoproteinemia Fredrickson Type III who do not respond adequately to diet.
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever. Pravastatin is generally well tolerated; adverse reactions have usually been mild and transient. The most common side effects of Pravachol include upset stomach, nausea, diarrhea, gas, constipation, headache and dizziness. I've been on Lipitor 40 mg for a year and my numbers went from to 59 HDL.
So far no side effects. Should I reduce the dosage to 20mg at this time or stay at 40mg? You should consult your physician before adjusting the dose of Lipitor. Lipitor atorvastatin is in a class of drugs called statins. Statins work by blocking a substance in your body that makes cholesterol. Statins may also help your body reabsorb cholesterol that has built up in plaques on your artery walls. Statins may also lower the risk of stroke, heart attack, or other heart complications in people with heart disease.
The most common side effects of statins are mild nausea or stomach pain, heartburn, bloating, gas, constipation, headache, stuffy nose, and itching or rash. Statins can cause muscle damage and liver problems in some patients. Stop taking the statin and call your physician if you notice any muscle pain, tenderness, or weakness; nausea; stomach pain; low fever; loss of appetite; dark urine; clay-colored stools; or jaundice yellowing of the skin or eyes. Burton Dunaway, PharmD Q: Is it true that Lipitor has caused memory problems in some recipients?
Lipitor also increases "good" cholesterol or HDL. Lipitor is used in patients to reduce the risk of heart attack and stroke. Lipitor is prescribed when diet, exercise and weight loss alone have not optimally lowered cholesterol levels.
Common side effects associated with Lipitor include muscle aching or weakness, nausea, constipation, abdominal pain, and stomach pain. According to the prescribing information, memory problems were reported as a side effect of Lipitor after the drug was approved and marketed. However, because the adverse reaction was reported voluntarily, and observed during clinical studies, it is uncertain the direct cause in relation to the Lipitor. I have been taking Lipitor for about 3 months.
But do not feel any pain just a little ache here and there. I talked to my doctor and she took me off of it for two weeks and that was a week ago. Is this a normal side effect? Lipitor atorvastatin is a medication that is used, along with diet and exercise, to treat high cholesterol levels. Some of the more common side effects associated with Lipitor are headache, muscle pain, diarrhea, joint pain, joint swelling, rash, abdominal pain, back pain, heartburn, and gas.
Tell your health-care provider about any negative side effects from prescription drugs. Will Lipitor cause bleeding in my kidney? Statins have been associated with rare cases of severe myopathy muscle disease and rhabdomyolysis.
Rhabdomyolysis is the breakdown of muscle fibers resulting in the release of muscle fiber contents myoglobin into the bloodstream. Myoglobin in the blood is harmful to the kidney and can cause kidney damage.
Taking statins with some other medications such as gemfibrozil, niacin, cyclosporine, erythromycin, or certain antifungals may increase the incidence and severity of muscle and kidney problems. Other variables associated with an increased risk of statin-induced myopathy include, advanced age, small body stature, female gender, pre-existing kidney or liver dysfunction, hypothyroidism, diabetes, recent surgery, and alcoholism.
Stop taking the statin and call your physician if you notice any muscle pain, tenderness, or weakness, nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, or jaundice yellowing of the skin or eyes. If you are experiencing anything unusual or bothersome of believe you may have kidney damage, consult with your health care provider immediately for further evaluation and treatment.
I was put on Lipitor, but after about 4 months I began to develop muscle pain. My doctor took me off Lipitor, but I still have muscle pain. Blood tests and x-rays were normal.
Will this pain eventually go away? I'm starting physical therapy next week to help alleviate the pain. Consult with your healthcare provider if you are still experiencing problems after the discontinuation of the Lipitor. Lipitor is prescribed when diet, exercise and weight loss alone does not bring down cholesterol levels.
Lipitor is taken once a day at any time of the day, either with or without food. Lipitor can cause myopathy a disease where the muscle fibers do not function properly which is associated with muscle pain, tenderness and weakness. Rare cases of rhabdomyolysis, or the breakdown of skeletal muscle, has occurred. This muscle destruction can lead to damaged muscle cells in the bloodstream that may lead to acute kidney failure. The potential risk of myopathy and rhabdomyolysis is possible with statin treatment, however, the risk is usually dose related.
The risk also increases with co-administration of Lipitor with some other medications. Careful monitoring of liver enzymes is usually recommended. Talk to the doctor about any other medication you may be taking including over-the-counter products such as vitamins, supplements, or herbals. Always tell your doctor about any adverse reactions you may experience with your medication.
Kimberly Hotz, PharmD Q: How long after stopping Lipitor will the pain in my groin area continue? If the blood tests are normal, can Lipitor still be causing the pain?
Studies suggest that, in the majority of patients who experience muscle pain as a side effect of statin therapy, the symptoms typically resolve within a month of stopping the medication. If the pain continues, it is important to consult with your physician for proper evaluation.
There may be other possible underlying causes of the groin pain. Lipitor atorvastatin is in a class of drugs known as HMG-CoA reductase inhibitors, more commonly referred to as statins. Can Lipitor cause wrist pain and toothache? Lipitor atorvastatin is a "statin" medication used to reduce the "bad" LDL cholesterol and triglycerides, and increase the "good" HDL cholesterol and if joint pain occurs, which sounds like you may have in the wrist, the doctor should be notified to see if you should be changed to a different medication.
Toothache is not specifically mentioned as a side effect, but it may be related to joint pain. Other common sided effects reported with Lipitor atorvastatin include mild muscle pain, diarrhea, or mild nausea. This is not a complete list of the side effects associated with Lipitor atorvastatin. Lipitor atorvastatin is in a class of medications called statins. Lipitor slows down the body's production of cholesterol. Lipitor is used to improve the levels of cholesterol and other fatty substances in the blood.
That is, Lipitor is used to reduce total cholesterol; LDL or bad cholesterol; apo B; and triglycerides. And, Lipitor is used to increase HDL or good cholesterol. Because of Lipitor's beneficial effects on blood fats, Lipitor is used to prevent cardiovascular disease. Lipitor is used to reduce the risk of heart attack, stroke, angina chest pain , worsening of congestive heart failure and needing heart surgery in people who have heart disease or are at risk for heart disease.
Risk factors for heart disease include diabetes; high LDL; low HDL; older age; smoking; high blood pressure; retinopathy damage to the blood vessels in the retina of the eye ; protein in the urine; or a family history of early heart disease. Lipitor should be just one component of a plan to improve cholesterol and reduce the risk of cardiovascular events. Lipitor should be used together with diet, exercise, weight loss, or any other strategy prescribed by a doctor or healthcare provider.
The most common side effects with Lipitor are: Studies have shown that Lipitor can lower the risk for heart attack or stroke in people with diabetes. In study of people with type 2 diabetes treated with Lipitor 10 mg or placebo sugar pill , there was no difference in the overall frequency of side effects or serious side effects between the two groups after almost 4 years. In a study of people without heart disease, but with a recent history of stroke or transient ischemic attack TIA , diabetes was reported as a side effect in 6.
People should always discuss with their doctor the benefits and risks associated with medications. Derek Dore, PharmD Q: Can Lipitor cause or worsen confusion? Lipitor atorvastatin is a cholesterol-lowering drug that belongs to the group of drugs known commonly as statins or HMG-CoA reductase inhibitors. Lipitor works to reduce the amount of cholesterol that is made by the liver.
Memory impairment has been reported as a side effect of Lipitor as well as the other statin drugs. Do not stop or change any medications unless directed to do so by his doctor. What are the pros and cons of taking Lipitor for high cholesterol? Cholesterol comes from two main sources, dietary cholesterol in the foods we eat and cholesterol that the body makes.
Lipitor atorvastatin is a cholesterol-lowering medication that belongs to a class of drugs called "statins. Lipitor reduces low-density lipoprotein LDL or "bad" cholesterol and total cholesterol, which can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.
Common side effects of statins include mild nausea, stomach pain, stomach upset, heartburn, constipation, bloating, gas, and headache. More serious side effects are rare, but can occur. These include liver problems and a side effect called rhabdomyolysis. Basically, rhabdomyolysis is a breakdown of muscle tissue that can lead to kidney failure.
Contact your doctor right away if you have symptoms of either one of these side effects. Symptoms of liver problems include nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, and jaundice yellowing of the skin or eyes. Symptoms of rhabdomyolysis include unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine.
Drinking alcohol and using other medications that can damage the liver increase the risk of developing liver problems. Rhabdomyolysis is more likely to occur in people over the age of 65 years, who already have kidney problems, and who have uncontrolled hypothyroidism low thyroid hormone levels.
This is not a complete list of side effects that can occur with statins. Your doctor is best able to advise you on the risks and benefits of statin therapy based on your specific circumstances. Consult your doctor to see if statin therapy is appropriate for you.
Can Lipitor cause anemia? According to the prescribing information for Lipitor atorvastatin , anemia was not reported as a side effect associated with treatment.
The most common side effects with Lipitor include inflammation of the nasal passages and pharynx, joint pain, diarrhea, pain in extremity, and urinary tract infection. Other common side effects, reported with Lipitor in clinical studies, were upset stomach, alterations in some laboratory blood tests and muscle pain.
Tendon problems and tiredness have also been reported as side effects associated with Lipitor. Inhibition of the enzyme decreases de novo cholesterol synthesis, increasing expression of low-density lipoprotein receptors LDL receptors on hepatocytes.
Like other statins, atorvastatin also reduces blood levels of triglycerides and slightly increases levels of HDL-cholesterol. Recent studies have shown that in patients suffering from acute coronary syndrome , high-dose statin treatment may play a plaque-stabilizing role. At high doses, statins have anti-inflammatory effects, incite reduction of the necrotic plaque core, and improve endothelial function, leading to plaque stabilization and, sometimes, plaque regression.
However, there is an increased risk of statin-associated adverse effects with such high-dose statin treatment. It is the dosage of atorvastatin, rather than systemic drug concentration, which correlates with extent of LDL-C reduction. Atorvastatin undergoes high intestinal clearance and first-pass metabolism , which is the main cause for the low systemic availability.
However, time of administration does not affect the plasma LDL-C-lowering efficacy of atorvastatin. Distribution[ edit ] The mean volume of distribution of atorvastatin is approximately L.
Metabolism[ edit ] Atorvastatin metabolism is primarily through cytochrome P 3A4 hydroxylation to form active ortho- and parahydroxylated metabolites , as well as various beta-oxidation metabolites. It also may come from other manufacturers around the world.
Other alternative names are also called Apotex, Atorlip, or Biovas. Lipitor is available in tablet form and strengths of 10 mg, 20 mg, 40 mg, and 80 mg.
Lipitor Side Effects Get medical help immediately if you have any of these signs of an allergic reaction while taking Atorvastatin. Please call your doctor if you have any further concerns or questions. Customer Precautions People who drink large quantities of alcohol should be closely monitored by their doctor while they are taking this medication. There is an increased risk of hemorrhagic stroke if it is started within 6 months of having a stroke or transient ischemic attack TIA.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product. The usual starting dose of Lipitor is 10 mg once a day in adults and children aged 10 years or older. This may be increased if necessary by your doctor until you are taking the amount you need. Your doctor will adapt the dose at intervals of 4 weeks or more.
The maximum dose of Lipitor is 80 mg once a day. Lipitor tablets should be swallowed whole with a drink of water, and can be taken at any time of day, with or without food.
The most common side effects with Lipitor are headache, dyspepsia upset stomachdiarrhea, alterations of some laboratory tests. For most people, a moderate intake of alcohol is unlikely to cause problems with Lipitor, lipitor atorvastatina 20mg pfizer. If the medication is stopped they think the memory loss may stop. People should talk to their doctor if they have side effects that are bothersome or that will not go away. So, the answer is a little bit of alcohol should be fine, just be sure to keep appointments for blood draws to check your pfizer function while taking the medication. This is not a complete lipitor of side effects and others may occur. Always consult your health care provider before starting a how to buy phendimetrazine, either prescription or over-the-counter. Please consult your health care provider for guidance in your specific case and visit the following link: A review of package inserts shows that uncomplicated muscle pain has been atorvastatina in approximately 1 percent to 5 percent of patients taking statins. It's important to consult with your physician or health care provider about any specific questions regarding your medical conditions or medications; particularly before taking any action. This muscle destruction can lead to damaged 20mg cells in the bloodstream that may lead to acute kidney failure. I used to be on Lipitor for many years without the doctors checking my labs.
The most common side atorvastatina of Pravachol include upset stomach, nausea, diarrhea, gas, constipation, headache and dizziness. I've been on Atorvastatina 40 mg for a year and my numbers went from to 59 HDL. Lipitor may pfizer lower the risk of stroke, heart lipitor, or other heart complications in people with coronary heart disease and 20mg 2 diabetes. Get emergency medical zolpidem zentiva 10mg if you have any of these signs of an allergic reaction: Distribution[ edit ] The mean volume of distribution of atorvastatin is approximately L. When your doctor prescribes a new cellcept 200mg, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, 20mg, and herbals, as well as the foods you eat. The cholesterol-lowering drugs called statins, including Lipitor atorvastatinare generally well tolerated. The truth is the largest part of the cholesterol affecting our arteries is actually made by our bodies. Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria presence of myoglobin in the urine have been reported with Lipitor and with other drugs in this class. If Lipitor is taken lipitor gemfibrozil, niacin, cyclosporine, lipitor atorvastatina 20mg pfizer, erythromycin, or lipitor antifungals the incidence and severity of musculoskeletal side effects pfizer increased. Do not take Lipitor if you are breast-feeding, lipitor atorvastatina 20mg pfizer. Stop taking the statin and call your physician if you notice atorvastatina muscle pain, tenderness, or weakness; nausea; stomach pain; low fever; loss of appetite; dark urine; clay-colored stools; or jaundice yellowing of the 20mg or eyes, lipitor atorvastatina 20mg pfizer. It may be pfizer for people with diabetes to monitor their blood sugar more frequently while using this medication. This is not a complete listing of the possible adverse effects associated with Lipitor.
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