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It is a good idea to write down how much quick-acting morphine you are using each day. Your doctor can then use this information to increase the dose of your slow-release morphine in order to keep you pain-free. One or two are taken as required, up to a maximum of four times a day. It may come in combination with paracetamol. You would normally take one or two as required up to a maximum of four times a day. What are the possible side-effects? As with all medicines, opioids have a number of possible side-effects.

In general, the stronger the opioid, the more likely you are to have side-effects. The most common side-effects are constipation, feeling sick nausea and drowsiness. Constipation - when you start treatment with an opioid, your doctor will usually also prescribe a laxative. Laxatives help to ease and prevent constipation by softening the poo stools , making it easier to pass, or they stimulate your bowel to push the stools along more quickly.

Nausea - feeling sick is a common side-effect when you first start taking an opioid. This usually passes after a week or so, once your body gets used to this medicine. Your doctor will prescribe an anti-sickness medicine an anti-emetic if you feel sick. Tell your doctor if sickness lasts for more than a week. Changing to a different opioid may help. Join wool at side. Pattern to the last 2 stitches. K or P 2 together. Continue in pattern until shoulder measures about 2 3, 4 inches from the bound off stitches at the neck edge.

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Side Tabs Make one tab on each side. Drugs that are injected include morphine and heroin, less commonly other opioids. Stimulants like cocaine or methamphetamine may also be injected. In rare cases, users inject other drugs. Many psychoactive drugs can be or have been specifically designed for sublingual administration, including barbiturates , benzodiazepines, [37] opioid analgesics with poor gastrointestinal bioavailability, LSD blotters, coca leaves, some hallucinogens.

This route of administration is activated when chewing some forms of smokeless tobacco e. Intravenous route is the most efficient, but also one of the most dangerous. Nasal, rectal, inhalation and smoking are safer.

The oral route is one of the safest and most comfortable, but of little bioavailability. Depressants[ edit ] Depressants are psychoactive drugs that temporarily diminish the function or activity of a specific part of the body or mind. Examples of these kinds of effects may include anxiolysis, sedation, and hypotension. Depressants are widely used throughout the world as prescription medicines and as illicit substances.

Depressants exert their effects through a number of different pharmacological mechanisms, the most prominent of which include facilitation of GABA or opioid activity, and inhibition of adrenergic , histamine or acetylcholine activity. Some are also capable of inducing feelings of euphoria a happy sensation. Stimulants or "uppers", such as amphetamines or cocaine , which increase mental or physical function, have an opposite effect to depressants. Antihistamines[ edit ] Antihistamines or "histamine antagonists" inhibit the release or action of histamine.

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