Mebendazole usp 500mg

Consult drug interactions database for more detailed information. Monitoring Parameters Periodic hematologic, hepatic, and renal function; check for helminth ova in feces within weeks following the initial therapy Pregnancy Risk Factor C Pregnancy Considerations Adverse events have been observed in animal reproduction studies.

Based on available data, adverse pregnancy outcomes have not been observed following use in pregnancy Diav-Citrin ; Gyorkos Treatment of pinworm in pregnancy may be considered; however, the CDC suggests postponing therapy until the third trimester when possible CDC During this hospital stay, were you given any medicine that you had not taken before?

Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?

This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions. Keep your fingernails short and clean, and avoid biting your nails or sucking your fingers. Have a separate towel for each member of your family to use. Change and wash your clothing and bedding frequently.

Can mebendazole cause problems? Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with mebendazole.

You will find a full list in the manufacturer's information leaflet supplied with your medicine. Mebendazole side-effects What can I do if I experience this? Tummy abdominal discomfort, diarrhoea, wind If troublesome, speak with your doctor or pharmacist If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store mebendazole Keep all medicines out of the reach and sight of children. Store in a cool, dry place, away from direct heat and light. Important information about all medicines If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Archived from the original on 8 January Retrieved 8 January McGraw-Hill, New York. Archived from the original on 22 February Retrieved 25 January Harrison's Principles of Internal Medicine, 18th ed.

Since the eggs can live only in warm soil, they are found most often where the soil never freezes in winter. People living or traveling in areas with warm winters may have these infections. The eggs in the soil are usually carried to the mouth on food or by contact with dirty hands. In the case of hookworms a pre-adult form of the worm actually penetrates the skin usually the foot and burrows its way into the bloodstream.

Once inside the body, they grow and breed inside the bowel. New eggs are released in the feces. Indicated surgical procedures should be performed in conjunction with metronidazole tablet therapy. In a mixed aerobic and anaerobic infection, antimicrobials appropriate for the treatment of the aerobic infection should be used in addition to metronidazole tablets.

In the treatment of most serious anaerobic infections, the intravenous form of metronidazole is usually administered initially. This may be followed by oral therapy with metronidazole tablets at the discretion of the physician.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of metronidazole tablets and other antibacterial drugs, metronidazole tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. In patients with trichomoniasis, metronidazole tablets are contraindicated during the first trimester of pregnancy. WARNINGS Convulsive Seizures and Peripheral Neuropathy Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, have been reported in patients treated with metronidazole.

The appearance of abnormal neurologic signs demands the prompt discontinuation of metronidazole therapy. Metronidazole should be administered with caution to patients with central nervous system diseases. Accordingly, for such patients, doses below those usually recommended should be administered cautiously. Known or previously unrecognized candidiasis may present more prominent symptoms during therapy with metronidazole and requires treatment with a candicidal agent.

Prescribing metronidazole tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of development of drug-resistant bacteria.

Information for Patients Alcoholic beverages should be avoided while taking metronidazole tablets and for at least one day afterward. Patients should be counseled that antibacterial drugs including metronidazole tablets should only be used to treat bacterial infections. They do not treat viral infections e. When metronidazole tablets are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed.

Skipping doses or not completing the full course of therapy may 1 decrease the effectiveness of the immediate treatment and 2 increase the likelihood that bacteria will develop resistance and will not be treatable by metronidazole tablets or other antibacterial drugs in the future. Laboratory Tests Metronidazole is a nitroimidazole and should be used with caution in patients with evidence of or history of blood dyscrasia.

A mild leukopenia has been observed during its administration; however, no persistent hematologic abnormalities attributable to metronidazole have been observed in clinical studies. Total and differential leukocyte counts are recommended before and after therapy for trichomoniasis and amebiasis, especially if a second course of therapy is necessary, and before and after therapy for anaerobic infections. Drug Interactions Metronidazole has been reported to potentiate the anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time.

This possible drug interaction should be considered when metronidazole is prescribed for patients on this type of anticoagulant therapy. The simultaneous administration of drugs that induce microsomal liver enzymes, such as phenytoin or phenobarbital, may accelerate the elimination of metronidazole, resulting in reduced plasma levels; impaired clearance of phenytoin has also been reported. The simultaneous administration of drugs that decrease microsomal liver enzyme activity, such as cimetidine, may prolong the half life and decrease plasma clearance of metronidazole.

In patients stabilized on relatively high doses of lithium, short term metronidazole therapy has been associated with elevation of serum lithium and, in a few cases, signs of lithium toxicity. Serum lithium and serum creatinine levels should be obtained several days after beginning metronidazole to detect any increase that may precede clinical symptoms of lithium intoxication.

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